Menthol is an organic compound made synthetically or obtained from the oils of corn mint, peppermint, or other mints. It is a waxy, crystalline substance, clear or white in color, which is solid at room temperature and melts slightly above. Menthol is included in many products, and for a variety of reasons. These include:
In nonprescription products for short-term relief of minor sore throat and minor mouth or throat irritation. As an antipruritic to reduce itching. As a topical analgesic, it is used to relieve minor aches and pains, such as muscle cramps, sprains, headaches, and similar conditions, alone or combined with chemicals such as camphor, eucalyptus oil or capsaicin. In Europe, it tends to appear as a gel or a cream, while in the U.S., patches and body sleeves are very frequently used. As a penetration enhancer in transdermal drug delivery. In decongestants for chest and sinuses (cream, patch, or nose inhaler). In certain medications used to treat sunburns, as it provides a cooling sensation (then often associated with aloe). In aftershave products to relieve razor burn. As a smoking tobacco additive in some cigarette brands, for flavor, and to reduce throat and sinus irritation caused by smoking. Menthol also increases nicotine receptor density. Increasing the addictive potential of tobacco products. Commonly used in oral hygiene products and bad-breath remedies, such as mouthwash, toothpaste, mouth, and tongue sprays, and more generally as a food flavor agent, such as in chewing gum and candy. As a pesticide against tracheal mites of honeybees. In perfumery, menthol is used to prepare menthyl esters to emphasize floral notes (especially rose).
Product | Menthol Crystal TL grade |
Grade | IP/BP/USP |
Reference | IP/USP Pass |
Description | Colorless, hexagonal crystals, white crystals, usually needle like, odor, pleasant and peppermint like. |
Identification | Complies |
Solubility | Slightly soluble in water, very soluble in alcohol, in chloroform and in solvent ether |
Specific rotation | -49® |
Nonvolatile residue | 0.0310 % w/w <0.05 % |
Readily oxidizable substance | Complies |
Melting range | 42.5 C Limit 41 to 44 |
Total menthol Content | >99.5 % |